Q. What is the function of Bile?
Solution:
Bile is a yellow-green fluid that is made by the liver, stored in the gallbladder and passes through the common bile duct into the duodenum where it helps digest fat. The principal components of bile are cholesterol, bile salts, and the pigment bilirubin.
An imbalance between these components of bile leads to the formation of gallstones. Gallstones can thus be composed of different materials. Cholesterol gallstones form when there is an imbalance between the amounts of cholesterol and the bile salts. Cholesterol is normally kept in liquid form by the dissolving action of the bile salts.
An increased amount of cholesterol in the bile overwhelms the dissolving capacity of the bile salts and leads to the formation of cholesterol gallstones. Similarly, a deficiency of bile salts promotes cholesterol gallstone formation. Pigment gallstones are frequently associated with chronic infection in the bile, especially in certain Asian countries where parasitic infection of the bile ducts is common.
Patients with blood diseases that cause excessive breakdown of red blood cells can have increased amounts of bilirubin (the breakdown product of red cells) in the bile, thus causing bilirubin gallstone formation.
Bile increases the absorption of fats, it is an important part of the absorption of the fat-soluble substances, such as the vitamins A, D, E, and K. Besides its digestive function, bile serves also as the route of excretion for bilirubin, a byproduct of red blood cells recycled by the liver.
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