Q. When viruses attack the bacteria, it in turn protect itself by fragmenting viral DNA with

A
Ligase
B
Endonuclease
C
Exonuclease
D
Gyrase
Solution:
  • Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain.
  • Some, such as deoxyribonuclease I, cut DNA relatively nonspecifically without regard to sequence.
  • Many, typically called restriction endonucleases or restriction enzymes, cleave only at very specific nucleotide sequences.
  • Endonucleases differ from exonucleases, which cleave the ends of recognition sequences instead of the middle (endo) portion.
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