Kerala Dewasom Recruitment Board is all set to conduct the Pharmacist Grade-II ( Category: 25/2020) written exam for the Guruwayoor Dewasom Board. The KDRB Pharmacist Grade 2 Syllabus 2021 includes topics like general awareness and pharmacology. The exam is scheduled for April 25, 2021, Sunday for all eligible applicants.
KDRB Pharmacist Grade 2 Syllabus 2021
Kerala Dewasom Recruitment Board has published the detailed syllabus for the Pharmacist Grade-2 post. The KDRB Pharmacist Grade 2 written test will be conducted for 02 hours duration for 100 marks with 100 objective type questions.
General Knowledge, Current affairs, Renaissance in Kerala, Temple affairs
- Important International, National and Regional events in the field of Economy, Science and Technology, Sports and Games, Politics, Arts and Culture, Cinema.
- Geographical features of India with special emphasis on Kerala. Climate, Rivers. Major River Projects, Tourist Destinations etc.
- Salient features of Indian Constitution-Fundamental Rights and Fundamental Duties-Constitutional bodies, Executive, Legislature, Judiciary at Union and State level.
- Institutions of National importance in the field of Health Care, Education, Agriculture Research, Science and Technology, Management Studies, Information Technology. Space Research and Space Exploration.
- Social Service, Social welfare, Social security-Legislations. Schemes of Central and State Governments. Right to information. Food Security Act.
- Major environmental Acts in India, Various Employment Guarantee Programmes, Pension
Schemes of Central and State Governments.
- The National and State Women Commissions. National and State Human Rights Commissions. Lokpal, Ombudsman. National and State Institutions for the Protection of Women and Child rights. State Literacy Mission. Kerala Social Security Mission. Haritha Kerala Mission. Kudumbasree.
- Kerala’s contribution to the field of Sports and Games. Famous sports Personalities – Achievements in National and International events. Olympians, Arjuna Award winners.
- Factors contributing to Corruption. – Anti Corruption laws in India. Constitutional Provisions to check Corruption. Central Bureau of Investigation, Enforcement Directorate, Central Vigilance Commission, National Investigating Agency, State Vigilance and Anticorruption Bureau–Constitution, Powers, Functions
- Democratic decentralisation in India in general and Kerala in particular. Methods, Benefits and objectives of Decentralisation. Local Self Governments – Rural and Urban–Powers and Functions.
- Road Safety and Safety measures. General Awareness of Traffic rules and regulations. Traffic offences. Traffic rules enforcement Authorities. Web application for Online vehicle registration and Driving License –Motor vehicles (Amendment) Act 2019. Important recommendations.
- Kerala Renaissance. Social reformers. Women Emancipation. Various Revolts and Agitations. Anti caste Movements. Temple Entry movement. Temple Entry Proclamation. Malabar rebellion of 1921. Pazhassi revolt. Left Movements. Awakening through Literature. Important Literary Figures. Purogamana Sahithya
Prasthanam, Nataka Prasthanam, Library Movements. etc
- Temple Affairs – Famous Temples in Kerala, Hindu customs and Traditions – Holy books of Hinduism. Basic knowledge. Great Indian Spiritual leaders, Saints. Thinkers and Philosophers. Various Devaswom Boards – Kerala Devaswom Recruitment Board – Formation, Powers, Responsibilities, Hierarchical setup.
KDRB Pharmacist Grade 2 Syllabus: Pharmaceutics
- Various dosage forms. Classification with examples – their relative applications. New drug delivery systems. Introduction to Pharmacopoeias with special reference to the Indian Pharmacopoeia. Metrology-System of weights and measures.
- Percentage calculations and adjustment of products. Use of allegation method in calculations and adjustment of products. Use of allegation method in calculations. Isotonic solutions.
- Packages of pharmaceuticals – Desirable features of a container and types of containers. Study of glass & plastics as materials for containers and rubber as a material for closure their merits and demerits.
- Introduction to aerosol packaging.
- Extraction and Galenicals, Concept of sterilization and its differences from disinfection. Detailed study of Sterilization with moist heat, dry heat sterilization, Sterilization by radiation, Sterilization by filtration and
Gaseous sterilization. Aseptic techniques-Applications of the sterilization process in hospitals particularly concerning surgical dressings and intravenous fluids. Precautions for safe and effective handling of sterilization equipment. Study of immunological products like sera, vaccines, toxoids & their preparations.
- Processing of Tablets; different type of compressed tablets and their properties. The process involved in the production of tablets; Tablets excipients; Defects in tablets; Evaluation of Tablets; Physical standards including Disintegration and Dissolution. Tablet coating-sugar coating; films coating, enteric coating and micro-encapsulation.
- Processing of Capsules-hard and soft gelation capsules; different sizes of capsules, filling of capsules; handling and storage of capsules. Special applications of capsules. Prescriptions-Reading and understanding of prescriptions; Latin terms commonly used Calculations involved in dispensing. Incompatibilities in prescriptions-study of various types of incompatibilities-physical, chemical and therapeutic. Posology-Dose and dosage of drugs, factors influencing dose, calculations of doses based on age, sex, surface area and veterinary doses. Methods of preparation with theoretical and practical aspects, use of appropriate containers and closures, special labelling requirements and storage conditions of Powders, Liquid oral, Gargles Syrups Mouth Washes, Throat-paints, Elixirs, Douches, Ear Drops, Nasal drops, Sprays, Liniments & Lotions.
- Biphasic Liquid Dosage Forms: Suspensions, Emulsions, Semi-Solid Dosage forms Ointments: Pastes,
Jellies: Suppositories and pessaries.
- Dental and cosmetic preparations: Introduction of Dentrifrices, facial cosmetics, Deodorants, Antiperspirants, shampoo, Hair dressings and Hair removers. Sterile Dosage forms parenteral dosage forms. Ophthalmic products.
Pharmaceutical organic compounds covering Important physical and chemical properties, medicinal and pharmaceutical uses, storage conditions and chemical incompatibility of:
- INORGANIC Acids, bases and buffers, Antioxidants,
Gastrointestinal agents, Acidifying agents-Antacids-Combinations of antacid preparations.
Protective and adsorbents, Saline cathartics.
- Topical Agents Protective, Antimicrobials and Astringents. Inorganic Dental Products-Inhalants-Oxygen, Carbon dioxide, Nutritious Oxide.
- Respiratory stimulants-Expectorants and Emetics-Antidotes. Major Intra and Extracellular
electrolytes. Electrolytes used for replacement therapy – Sodium chloride and its
- Potassium chloride and its preparations. Physiological acid-base balance and electrolytes used-Combination of oral electrolyte powders and solutions. Radiopharmaceuticals and contrast media-Radio activity-Alpha; Beta and Gamma Radiations, Biological effects of radiations.
- Radio isotopes-their uses, Storages and precautions with special reference to the official preparations. Radio opaque contrast media Barium sulfate.
- Quality control of Drugs and pharmaceuticals-sources of impurities in pharmaceuticals.
- Limit tests for Arsenic, Chloride, Sulfate, Iron and Heavy Metals. Introduction to nomenclature refers to a heterocyclic system containing up to 3 rings. Uses, Important physical and chemical properties, stability and storage conditions and the different type of pharmaceutical formulations of the following drugs and their popular brand names.
- Antiseptics and disinfectants-Proflavine, Benzalkonium chloride, Cetrimide, Phenol, Chloroxylenol, Formaldehyde solution Hexachlophone, Nitrofurantoin. SulphonamidesSulphadiazine, Sulphaguanidine, Phthalylsulphathiazole, Succinylsulphathiazole, Sulfadimethoxine, sulphamethoxypyridazine, Co-trimoxazole, sulfacetamide Antileprotic Drugs-Clofazimine, Thiambutosone, Dapsone, solapsone, Anti-tubercular Drugs-Isoniazid, PAS, Streptomycin, Rifampicin, Ethambutol, Thiacetazone, Ethionamide,
cycloserine, pyrazinamide. Antimonic and Athelminic Druga-Emetine, Metronidazole, Halogenated hydroxyquinolines, Diloxanide, furoate, Mebendazole D.E.C. AntibioticsBenzyl penicillin, phenoxy methyl penicillin, Bentamicin penicillin, Ampicillin.
- Cloxacillin, Carbenicillin, Gentamicin, Neomycin, Erythromycin, Tetracycline, Cephalexin, Cephaloridine, Cephalothin, Griseofulvin, Chloramphenicol. Antifungal agents-Tolnaftate, Nystatin Amphotericin, Antimalarial Drugs-Chloroquine, Amodiaquine, Pimaquite, Proguanil, pyrimethamine, Quinine, Trimethoprim. Tranquilizers-Chlorpromazine, Prochlorperazine, Trifluoperazine, Thiothixene, Haloperidol, etc.
- Anti-Neoplastic Drugs – Actinomycin, Azathrioprie, Busulphan, Chloramubucil, Cisplatin, Cyclophosphamide, Daunorubicin Hydrochloride, Fluorouracil, Mercaptopurine, Methotrexate, Mytomicin.
KDRB Pharmacist Grade 2 Syllabus: Pharmacognosy
- History and scope of Pharmacology including the indigenous system of medicine.
- Adulteration and drug evaluation; the significance of pharmacopoeial standards. Occurrence, distribution of organoleptic evaluation, chemical constituents including tests wherever applicable and therapeutic efficacy of following categories of drugs. (a) Laxatives – Alboes, Rhubarb, Castor oil, Ispaghula Senna. (b) Cardiotonics – Digitalis, Arjuna. (c) Carminatives & GI regulators – Umbelliferous fruits, Coriander, Fennel, Ajowan, Cardamom, Ginger, Black pepper, Asafoetida, Nutmeg, Cinnamon, Clove. (d) Astringents –
Catechu. (e) Drugs acting on the nervous system – Hysocyamus, Belladonna, Aconite, Ashwagandha, ephedra, Opium, Cannabis, Nux-vomica. (f) Antithypertensive-Rauwolfia. (g) Antitussives – Vasaka, Tolu balsam, Tulsi. (h) Antirheumatics- Guggal, Colchicum. i) Antitumous – Vinca, (j) Antileprotics-Chaulmoorga oil. (k) Antidiabetics- Pterocarpus, Gymnema Sylvestre. (l) Diuretics – Gokhru, Punarnava. (m) Antidysentrics- Ipecacunha. (n) Antiseptics and disinfectants – Benzoin, Myrrh, Neem, Curcuma (o) Antimalarials – Cinchona. (p) Oxytocics – Ergot. (q) Vitamins- Shark liver oil and amla (r) EnzymesPapaya, Dissate, Yeast. (s) perfume sand flavouring agents- peppermint oil, Lemon oil, Orange oil, lemongrass oil, sandalwood. Miscellaneous – Liquorice, Garlic, Picrohiza Dirsorea, Linseed, Shatavari, sankhpushp, pyrethrum, Tobacco,
- Study of source, preparation and identification of fibres used in sutures and surgical dressings-cotton, silk,
wool and regenerated fibres. Gross anatomical studies of -senna, Datura, cinchona, fennel,
clove, ginger, Nuxvomica & ipecacuanha.
Biochemistry and Clinical Pathology
- Introduction to biochemistry. Brief chemistry and role of proteins, polypeptides and amino acids, classification, Qualitative tests, Biological value, Deficiency diseases.
- Carbohydrates: Brief chemistry and role of carbohydrates, classification, qualitative tests, Diseases related to carbohydrate metabolism. Lipids: Brief chemistry and role of lipids, classification and qualitative tests. Diseases related to lipids metabolism.
- Vitamins: Brief chemistry and role of vitamins and coenzymes. Role of minerals and water in the life process.
- Enzymes: Brief concept of enzymatic action. Factors affecting it. Therapeutics: Introduction to the pathology of blood and urine. Lymphocytes and platelets, their role in health and disease. Erythrocytes-Abnormal cells and their significance. Abnormal constituents of urine and their significance in diseases.
Human Anatomy and Physiology
- Structure of cell, the function of its components with special reference to mitochondria and
microsomes. Elementary tissues: Elementary tissues of the body, i.e. epithelial tissue, muscular tissue, connective tissue and nervous tissue.
- Skeletal System: Structure and function of Skelton, Classification of joints and their function. Joint disorders.
Cardiovascular System: Composition of the blood, functions of blood elements. Blood group and coagulation of blood. Brief information regarding disorders of the blood. Name and functions of lymph glands. Structure and functions of various parts of the heart. The arterial and venous system with special reference to the names and positions of main arteries and veins. Blood and its recording. Brief information about cardiovascular disorders.
- Respiratory system: Various parts of the respiratory system and their functions, structure and
functions of the Kidney. Physiology of urine formation. Pathophysiology of renal diseases
- Muscular System: Structure of skeletal muscle, physiology of muscle contraction. Names, positions, attachments and functions of various skeletal muscles. Physiology of neuromuscular junction. Central
- Nervous System: Various parts of the central nervous system, brain and its parts, functions and reflex action. Anatomy and physiology of automatic nervous system. Sensory Organs: elementary knowledge of structure and functions of the organs of taste, smell, ear, eye and skin. Physiology of pain.
- Digestive System: names of various parts of the digestive system and their functions. Structure and functions of the liver. Physiology of liver, physiology of digestion and absorption.
- Endocrine System: Endocrine glands and Hormones. Location of glands, their hormones and functions, Pituitary, Thyroid Adrenal and Pancreas. Reproductive system: Physiology and Anatomy of Reproductive system.
Health Education and Community Pharmacy
- Concept of health: Definition of physical health, mental health, social health, spiritual health determinants of health, indicatory of health, the concept of disease, the natural history of diseases, the disease agents, concept of prevention of diseases.
- Nutrition and health: Classification of foods, requirements, diseases induced due to deficiency of proteins,
vitamins and minerals-treatment and prevention.
- Demography and family planning: Demography cycle, fertility, family planning, contraceptive methods, behavioural methods, natural family planning methods, chemical methods, mechanical methods, hormonal contraceptives, population problem of India.
- First aid: Emergency treatment in shock, snake-bite, burns, poisoning, heart disease, fractures and resuscitation methods. Elements of minor surgery and dressings. Light solid waste disposal and control-medical entomology, arthropod-borne diseases and their control. rodents, animals and diseases.
- Fundamental principles of microbiology: Classification of microbes, isolation, staining techniques of
organisms of common diseases.
- Communicable diseases: Causative agents, mode of transmission and prevention. Respiratory infections, chickenpox, measles, influenza, diphtheria, whooping cough and tuberculosis. Intestinal infection-poliomyelitis, Hepatitis, cholera, typhoid, food poisoning, Hookworm infection.
- Arthropod-borne infections-plague, Malaria, filariasis, Surface infection-Rabies, Trachoma, Tetanus, Leprosy,
- Sexually transmitted diseases-Syphilis, Gonorrhoea, AIDS. Non-communicable diseases: causative agents, prevention, care and control. Epidemiology: Its scope, methods, uses, dynamics of disease transmission.
- Immunity and Immunization: Immunological products and their dose schedule. Principles of disease control and prevention, hospital-acquired infection, prevention, prevention and control. Disinfection, types of disinfection procedures, for faeces, urine, sputum, room linen, dead-bodies, instruments.
Pharmacology & Toxicology
- Routes of administration of drugs, their advantages and disadvantages. Various process of absorption of drugs and the factors affecting them. Metabolism, distribution and exertion of drugs. Pharmacological classification of drugs.
- Drugs acting on the central Nervous system. General anaesthetics – adjunction to anaesthesia, intravenous anaesthetics.
- Analgesic antipyretics and non-steroidal Anti-inflammatory drugs – Narcotic analgesics.
- Antirheumatic and anti-gout remedies. Sedatives and Hypnotics, psychopharmacological agents.
- Anticonvusants, analeptivs. Centrally acting muscle relaxants and anti parkinsonism agents.
- Local anaesthetics. Drugs acting on the autonomic nervous system. Cholinergic drugs, Anticholinergic drugs, anticholinesterase drugs, Adrenergic drugs and adrenergic receptor blockers. Neurone blockers and ganglion blockers.
- Neuromuscular blockers, used in myasthenia gravis. Drugs acting on the eye: Mydiatrics drugs used in glaucoma. Drugs acting on respiratory system Respiratory stimulants, Bronchodilators, Nasal decongestants, Expectorants and Antitussive agents. Autocoids: physiological role of histamine and serotonin, Histamine and Antihistamines, prostaglandins.
- Cardiovascular drugs Cardiotonics, Antiarrhythmic agents, Anti-anginal agents, Antihypertensive agents,
Peripheral Vasodilators and drugs used in atherosclerosis.
- Drugs acting on the blood and blood-forming organs. Haematinics, coagulants and anticoagulants, Haemostatic, Blood substitutes and plasma expanders.
- Drugs affecting renal function – Diuretics and anti diuretics.
- Hormones and hormone antagonists-Hypoglycemic agents, Anti-thyroid drugs, sex hormones and oral contraceptives, corticosteroids. Drugs acting on digestive system carminatives, digest ants, Bitters, Antacids and drugs used in peptic ulcer, purgatives, and laxatives, Antidiarrohoels, emetics, Anti-emetics, Antispasmodics.
- Chemotherapy of microbial diseases. Urinary antiseptics, sulphonamides, penicillin, streptomycin, Tetracyclines and other antibiotics. Antitubercular agents, Antifungal agents, antiviral drugs, antileprotic drugs. Chemotherapy of protozoal diseases, Anthelmintic drugs, Chemotherapy of cancer.
- Disinfectants and antiseptics.
KDRB Pharmacist Grade 2 Syllabus: Pharmaceutical Jurisprudence
- Origin and nature of pharmaceutical legislation in India, its scope and objectives.
- Principles and significance of Professional Ethics.
- Critical study of the code of Pharmaceutical Ethics drafted by Pharmacy Council of India. Pharmacy Act, 1948, Drugs and Cosmetics Act, the 1940-General study of the Drugs and Cosmetics Act and the Rules thereunder.
- Definitions and salient features related to retail and wholesale distribution of drugs.
- The powers of Inspectors, the sampling procedures and the procedure and formalities in obtaining licenses
under the rule.
- Facilities to be provided for running a Pharmacy effectively. General study of the schedules with special reference to schedules C, CI, F, G, J, H, P and X and salient features of labelling and storage conditions of drugs.
- The Drugs and Magic Remedies (objectionable Advertisement) Act… Narcotic Drugs and psychotropic (substances Act, 1985- Brief introduction to the study of the following acts: Latest Drugs (price control) order in force. Poisons Act 1919 (as amended to date) Medicinal and Toilet preparations (Excise
Duties) Act, 1955 (as amended to date). Medical Termination of Pregnancy Act, 1971 (as amended to date).
Drug Store and Business Management
- Introduction to Elements for Economics and Management.
- Forms of Business Organizations. Channels of Distribution. Drug House Management-selection of Site, Space Lay-out and legal requirements.
- Importance and objectives of Purchasing, selection of suppliers, credit information, tenders, contracts and price determination and legal requirements thereto. Codification, handling of drug stores and other hospital supplies.
- Inventory Control-objects and importance, modern techniques like ABC, VED analysis, the lead time, inventory carrying cost, safety stock, minimum and maximum stock levels, economic order quantity, scrap and surplus disposal.
- Banking and Finance-Service and functions of the bank, Finance planning and sources of finance.
- Introduction to the accounting concepts and conventions. Double-entry Book-keeping. Different kinds of accounts. Cashbook, General Ledger and Trial Balance. Profit and Loss Account and Balance Sheet,
simple techniques of analyzing financial statements. Introduction to Budgeting.
Hospital & Clinical Pharmacology
- Hospital Pharmacy: Definition Functions and objectives of Hospital Pharmaceutical services, Location, Layout, flow chart of materials and men.
- Personnel and facilities requirements including types of equipment based on individual and basic needs Requirements and abilities required for Hospital pharmacists.
- The drug Distribution system in Hospitals. Manufacturing, Economical considerations, estimation of demand.
- Nomenclature and uses of surgical instruments and Hospital Equipment and health accessories. PTC (Pharmacy Therapeutic Committee) Hospital Formulary system.
- Drug Information service and Drug Information Bulletin.
- Surgical dressing like cotton, gauze, bandages and adhesive tapes including their pharmacopoeial tests for quality.
- Other hospital supply eg. IV sets, BG sets, Ryals tubes, Catheters, Syringes etc.
- Introduction of Clinical pharmacy practice-Definition, scope, Modern dispensing aspects. Pharmacists and patient counselling and advice for the use of common drugs, medication history.
- Common daily terminology used in the practice of medicine. Disease, manifestation and pathophysiology including salient symptoms to understand the disease like Tuberculosis, Hepatitis, Rheumatoid Arthritis, Cardio-vascular diseases, Epilepsy, Diabetes, Peptic Ulcer, Hypertension. Psychological parameters with
- Drug-drug interaction concerning analgesics, diuretics, cardiovascular drugs, Gastro intestinal agents. Vitamins and Hypoglycemic agents.
- Drug food interaction. Adverse Drug Reaction: Definition and significance. Drug-induced diseases and Teratogenicity. Drugs in Clinical Toxicity – Introduction, general treatment of poisoning, systemic antidotes, Treatment of insecticide poisoning, heavy metal poison, Narcotic drugs, Barbiturate, Organophosphorus poisons. Drug dependences, drug abuse, addictive drugs and their treatment complications.
- Bio-availability of drugs, including factors affecting it.
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