Kerala PSC Analyst Grade 3 Drugs Control Department

Table of Contents

The Kerala Public Service Commission has earlier invited online applications for the post of Analyst Grade 3 (Drugs Control Department). Further, the commission will soon release the examination dates for the above mentioned post. All the aspiring candidates must surely go through the syllabus before starting to prepare for the examination. In this article, read about Kerala PSC Analyst Grade 3 (Drugs Control Department) Syllabus 2020 in detail.

Attempt Free Current Affairs Mock Test

Kerala PSC Analyst Grade 3 Syllabus (Drugs Control Department)

Firstly, we shall divide the Analyst Grade 3 (DCD) Syllabus into 10 different modules. They are listed below:

Inorganic Chemistry- Pharmaceutical Chemistry I
Pharmaceutical Analysis I
Chemistry of Natural Products- Pharmaceutical Chemistry II
Pharmaceutical Jurisprudence
Pharmacognosy
Pharmacology-I & Biopharmaceutics
Pharmacology-I &Clinical Pharmacy
Medicinal Chemistry- Pharmaceutical Chemistry III
Pharmaceutical Analysis II
Pharmaceutics and Microbiology

Let us now have a detailed look at the different modules one by one.

Pharmaceutical Chemistry I (Inorganic Chemistry)

Introduction to Pharmacopoeia and monograph
Quality Control and test for purity.
Study of pharmaceutically important compounds
Theory of co-ordination compounds with special reference to application in Pharmacy and Pharmaceutical analysis
Test for purity of swelling property of bentonite, Acid neutralizing capacity of aluminium hydroxide gel, etc.
Determination of specific rotation of a compound, refractive index and partition co-efficient.

Pharmaceutical Analysis I

Neutralization titrations
Non-aqueous titrations
Precipitation titrations
Complexometric titrations
Oxidation – reduction titrations
Gravimetric analysis
Miscellaneous methods

Pharmaceutical Chemistry II (Chemistry of Natural Products)

Carbohydrates, Proteins and Amino acids
Terpenoids, Alkaloids and Glycosides
Vitamins and Purines
Fats and Oils
Steroids
Estimation

Pharmaceutical Jurisprudence

Introduction, Definition and scope of Forensic pharmacy. Pharmaceutical legislation in India and historical developments.
A detailed study (a) Pharmacy Act. (b) Drugs and Cosmetics Act. (c) Medicinal and Toilet preparations (Excise Duties) Act and Rules. (d) Narcotic Drugs and Psychotropic Substances Act. (e) Drugs and Magic Remedies (Objectionable Advertisements) Act.
A brief study of (a) Drugs Prices Control Order. (b) A.I.C.T.E. Act. (c) Patents Act. (d) Trade and Merchandise marks Act. (e) States Shops and Establishments Act. (f) Minimum Wages Act. (g) Factories Act. (h) Prevention of Food Adulteration Act and Rules. (i) Prevention of Cruelty to Animals Act. (j) Medical Termination of Pregnancy Act. (k) The Poisons Act
Drug tragedies.

Pharmacognosy

Study of the biological sources and traditional drugs.
Introduction to alternative systems of medicine.
Systematic study of source.
General techniques of biosynthetic studies and basic metabolic pathways.
Introduction, classification and study of different chromatographic methods and their applications.
Preparation of the extracts and various extraction techniques including supper critical fluid extraction.
Marine pharmacognosy, novel medicinal agents from marine sources.
Plant allergens and allergenic substances. Classification and preparation of allergenic extracts.
Biological sources, preparation, identification tests and uses of the following enzymes: Diastase, Papain, Bromalein, Maltase
Protein containing drugs: Gelatin, Collagen, spirulina
Introduction to herbal drug technology. Development and evaluation of herbal formulations.
Adulteration and evaluation of crude drugs.
Herbaceous health foods.
Herbal cosmetics – including classifications with examples.
Patenting of Herbal Drugs
Estimation of phytopharmaceuticals : Atropine, Quinine, Curcumine, Aloin, Caffeine.
Physicochemical evaluation of crude drugs and formulations including ash values, extractive values, refractive index.

Attempt Free Kerala PSC Previous Year Question Paper

Pharmacology-I & Biopharmaceutics

Pharmacology

General Pharmacology.
Drug dose & dosage: Fixed dose combination -Advantages & disadvantages.
Rational use of medications.
Pharmacogenetic variation in drug action
Principles of Toxicology.
Pharmacology of drugs in special groups- Pregnancy, lactation pediatrics and elderly.
Chrono pharmacology
Pharmacology of different classes of drugs.

Biopharmaceutics

Biotransformation – phase I and phase II reactions
Compartment models- Definition, One compartment model- IV Bolus, IV Infusion, Extra Vascular administration.
Non-linear pharmacokinetics- One compartment model IV Bolus administration, Michaelis Menten equation.
Measurement of Bioavailability- Cmax, t max, AUC. Design of single dose Bioequivalent study, dissolution and disintegration

Pharmacology-I & Clinical Pharmacy

Pharmacology

Measurements in pharmacology
Drug discovery and new drug development
Pharmacology of certain groups of drugs
Antimicrobial drugs & Chemotherapy
Immuno pharmacology.

Clinical Pharmacy

Drug & Poison information services
Clinical pharmacokinetics & individualization of drug therapy
Adverse drug reactions: Detection, monitoring & reporting of ADRs.
Definition and implications of Evidence based medicine, Practice based research & laboratory based research
Preparation of drug profiles, leaflets, packaging inserts.
Drug interactions: clinical significance, potentially dangerous interactions, role of pharmacist in identification, assessment and ways to overcome interactions.
Concept of Essential drugs and rational drug use.
Clinical management

Pharmaceutical Chemistry III (Medicinal Chemistry)

Basic Concepts and Applications of Prodrug Design
Study of Classification, Mechanism of Action, uses and Structure of selected drugs

Pharmaceutical Analysis II

Chromatography
Potentiometric titrations: Introduction, Electrochemical cells, half-cells, electrodes, measurement of potential and application in pharmaceutical analysis
Conductometric titrations: Basic concepts, different types of conductometric titrations, apparatus used and applications in Pharmaceutical Analysis.
Thermal Analysis: Basic Concepts and Applications in Pharmaceutical Analysis.
Polarography, Amperometry and Electrophoresis.
Turbidimetry and Nephelometry
Theoretical aspects, basic instrumentation, elements of interpretation of spectra.

Pharmaceutics and Microbiology

Pharmaceutics

Tablets Characteristics, advantages and disadvantages. Types of tablets, excipients, granulation methods and machinery involved.
Tablet coating: Types-sugar coating, film coating, compression coating, electrostatic and enteric coating.
Capsules: Advantages and disadvantages of capsules.
Sterile products
Pharmaceutical aerosols: components, propellants, containers, valves and actuators, types of aerosol systems, manufacture, quality control, pharmaceutical applications.
Surgical ligatures and sutures, types, Catgut-preparation and standardization. Cotton-absorbent and non-absorbent
Blood products and plasma.
Packaging materials. Types of glasses and plastics employed for packing and their evaluation.
Introduction, fundamentals of cosmetic science.
Controlled drug delivery systems
Process validation and performance evaluation.
Pharmaceutical calculations.

Microbiology

Introduction to the scope of microbiology, Microscopy-compound, dark field, phase contrast, UV, fluorescence and electron microscopy.
Classification of microbes and bacterial taxonomy.
Structure of bacterial cell.
Bacterial Nutrition, cultivation of bacteria.
Immunity
Control of microbes by Physical and Chemical methods
Antibiotics: Antimicrobial Spectrum and methods used for standardization, Fermentation technology.

Ace your Kerala PSC Exam Preparations with Entri!